19.02.2019 A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Genome‐, transcriptome‐ and proteome‐wide measurements provide insights into how biological systems are regulated. However, fundamental aspects relating to which human proteins exist, where they are expressed and in which...[more]

14.01.2019 Challenges in Clinical Metaproteomics

Challenges in Clinical Metaproteomics Highlighted by the Analysis of Acute Leukemia Patients with Gut Colonization by Multidrug-Resistant Enterobacteriaceae.[more]

07.12.2018 Alexander von Humboldt Fellowship

Congratulations to Dr. Yangyang Bian for being a awarded two-year Alexander von Humboldt Research Fellowship.[more]

01.06.2018 Systematic characterization of 21 post-translational protein modifications

To more broadly understand the LC-MS/MS characteristics of PTMs, we synthesized and analyzed ~5,000 peptides representing 21 different naturally occurring modifications of lysine, arginine, proline and tyrosine side chains and...[more]

03.04.2018 Mining the human tissue proteome for protein citrullination

Citrullination is a post-translational modification of arginine catalyzed by five peptidylarginine deiminases (PADs) in humans. The loss of a positive charge may cause structural or functional alterations and while the...[more]

05.02.2018 Peptide level turnover measurements enable the study of proteoform dynamics

The coordination of protein synthesis and degradation regulating protein abundance is a fundamental process in cellular homeostasis. Today, mass spectrometry-based technologies allow determination of endogenous protein turnover...[more]

21.12.2017 Richtzenhain-Preis for outstanding dissertation

We congratulate our former lab member Susan Kläger for being awarded with the "Richtzenhain-Preis" of the DKFZ (German Cancer Research Center) for her outstanding dissertation.[more]

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