02.05.2016 MALDI‐TOF and nESI Orbitrap MS/MS identify orthogonal parts of the phosphoproteome

In this study, we compared tandem mass spectrometry (MS/MS) on MALDI-TOF nESI Orbitrap instruments with respect to their ability to identify phosphopeptides from complex proteome digests.[more]

20.02.2016 Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors

The enzyme ferrochelatase (FECH) catalyzes the conversion of protoporphyrin IX into heme and was recently found to be an off-target of the BRAF inhibitor Vemurafenib, likely explaining the phototoxicity associated with this drug...[more]

09.12.2015 Ortner-Preis für WZW-Absolventin

Bei der Akademischen Jahresfeier der Technischen Universität München (TUM) wurde bekannt gegeben, welche TUM-Nachwuchsforscher 2015 zu den Besten zählen. Mit dabei ist Master-Absolventin Jana Zecha vom Lehrstuhl für Proteomik und...[more]

20.11.2015 Two Alexander von Humboldt Fellows

Congratulations to Anna Jarzab and Peng Yu for being a awarded two-year Alexander von Humboldt Research Fellowship![more]

30.09.2015 Bernhard awarded 2015 HUPO Award

On HUPO 2015, Bernhard was awarded the HUPO Discovery in Proteomic Sciences Award 2015. Congratulations![more]

17.09.2015 Evaluation of Kinase Activity Profiling Using Chemical Proteomics

Evaluation of Kinase Activity Profiling Using Chemical Proteomics: It has been suggested that the binding of kinases to affinity beads reflects a kinase’s activation status, a concept that is under considerable debate.[more]

26.05.2015 EPHA2 as a Mechanism of Acquired Resistance to EGFR Inhibitors

Chemical Proteomics Uncovers EPHA2 as a Mechanism of Acquired Resistance to Small Molecule EGFR Kinase Inhibition[more]

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